Informace o projektu
Self-assembly of amphiphilic peptides with helical character
(SAAP)
- Kód projektu
- GA14-12598S
- Období řešení
- 1/2014 - 12/2016
- Investor / Programový rámec / typ projektu
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Grantová agentura ČR
- Standardní projekty
- Fakulta / Pracoviště MU
- Přírodovědecká fakulta
In living organisms, a wide variety of peptides self-assemble into a range of structures, which can be vital or
lethal. The proposed project aims at elucidating key conditions and properties of self-assembly of amphiphilic
peptides with prolate shape. The key insight in the self-assembly is rationalization of the dependence of
aggregate morphology on the structure of building blocks. To explore the dependence, we will use computer
simulations with coarse grained models, which are computational affordable and at the same time contain
the essential features of building peptides. The obtained knowledge could provide a valuable information
for development of new peptide based materials, scaffolds, and therapeutics.
Publikace
Počet publikací: 14
2015
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Self-assembly of prolate patchy particles
Rok: 2015, druh: Další prezentace na konferencích
2014
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Physics of colloidal particles with heterogeneously patterned surfaces
Rok: 2014, druh: Další prezentace na konferencích
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Surface Effects on Aggregation Kinetics of Amyloidogenic Peptides
Journal of the American Chemical Society, rok: 2014, ročník: 136, vydání: 33, DOI
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Surface Effects on Aggregation Kinetics of Amyloidogenic Peptides
Rok: 2014, druh: Další prezentace na konferencích