doc. Mgr. Martin Trbušek, Dr.

Assistant professor, Section of Genetics and Molecular Biology

office: bldg. C13/323
Kamenice 753/5
625 00 Brno

phone:	+420 549 49 8131

Basic information

Supervision

Qualifications

Publications

Type

Total number of publications: 244

2013

Mutační analýza genu NOTCH1 u pacientů s chronickou lymfocytární leukemií

KANTOROVÁ Barbara MALČÍKOVÁ Jitka ŠMARDOVÁ Jana TRBUŠEK Martin BRYCHTOVÁ Yvona DOUBEK Michael MAYER Jiří POSPÍŠILOVÁ Šárka

Conference abstract

Year: 2013, type: Conference abstract
Ofatumumab added to dexamethasone in patients with relapsed of refractory chronic lymphocytc leukemia. Results from a phase II study of the czech leukemia study group for life

DOUBEK Michael BRYCHTOVÁ Yvona PANOVSKÁ Anna TRIZULJAK J. ŠEBEJOVÁ Ludmila STEHLÍKOVÁ Olga CHOVANCOVÁ Jana MALČÍKOVÁ Jitka ŠMARDOVÁ Jana PLEVOVÁ Karla VOLFOVÁ Pavlína TRBUŠEK Martin MRÁZ Marek MAJERČÁKOVÁ Denisa OBRTLÍKOVÁ Petra KARBAN Josef SMOLEJ Lukáš LINDTNEROVÁ Michaela OLTOVÁ Alexandra JELÍNKOVÁ Eva POSPÍŠILOVÁ Šárka MAYER Jiří

Conference abstract

Year: 2013, type: Conference abstract
Overview of available p53 function tests in relation to TP53 and ATM gene alterations and chemoresistance in chronic lymphocytic leukemia

TE RAA G. Doreen MALČÍKOVÁ Jitka POSPÍŠILOVÁ Šárka TRBUŠEK Martin MRÁZ Marek LE GARFF-TAVERNIER Maria MERLE-BERAL Helene LIN Ke PETTITT Andrew R. MERKEL Olaf STANKOVIC Tatjana VAN OERS Marinus H. ELDERING Eric STILGENBAUER Stephan ZENZ Thorsten KATER Arnon P.

Article in Periodical

Leukemia & Lymphoma, year: 2013, volume: 54, edition: 8, DOI
Reactivation of selected p53 mutants in B-cell tumor cell lines using targeted small molecules

JAŠKOVÁ Zuzana ŠEBEJOVÁ Ludmila POSPÍŠILOVÁ Šárka TRBUŠEK Martin

Conference abstract

Year: 2013, type: Conference abstract
Reaktivace vybraných p53 mutantů u B-buněčných nádorových linií prostřednictvím malých cílených molekul

JAŠKOVÁ Zuzana ŠEBEJOVÁ Ludmila POSPÍŠILOVÁ Šárka TRBUŠEK Martin

Conference abstract

Year: 2013, type: Conference abstract
SF3B1 mutations frequently occur with both ATM mutations and TP53 mutations in CLL patients

NAVRKALOVÁ Veronika MALČÍKOVÁ Jitka KANTOROVÁ Barbara ŠEBEJOVÁ Ludmila PLEVOVÁ Karla MRÁZ Marek DOUBEK Michael BRYCHTOVÁ Yvona ŠMARDOVÁ Jana MAYER Jiří POSPÍŠILOVÁ Šárka TRBUŠEK Martin

Conference abstract

Year: 2013, type: Conference abstract
Synthetic lethality in p53 mutated B-cell mylignancies: Chk-1 inhibition and DNA-PK inhibition effect in cell lines and primary CLL cells

ZEMANOVÁ Jana ŠEBEJOVÁ Ludmila PARUCH Kamil HYLSE Ondřej POSPÍŠILOVÁ Šárka MAYER Jiří TRBUŠEK Martin

Conference abstract

Year: 2013, type: Conference abstract
The BCR-ABL1 T315I mutation and additional genomic aberrations are dominant genetic lesions associated with disease progression in patients with chronic myelogenous leukemia resistant to tyrosine kinase inhibitor therapy.

MALČÍKOVÁ Jitka RÁZGA Filip JURČEK Tomáš DVOŘÁKOVÁ Dana ŽÁČKOVÁ Daniela TOŠKOVÁ Hana ŠEBEJOVÁ Ludmila ŠMARDOVÁ Jana OLTOVÁ Alexandra VAŇKOVÁ Gabriela JURAČKOVÁ Lenka TRBUŠEK Martin POSPÍŠILOVÁ Šárka MAYER Jiří RÁČIL Zdeněk

Article in Periodical

Leukemia & Lymphoma, year: 2013, volume: 54, edition: 9, DOI
The expression of a single microRNA -miR-34a - is a reliable marker for impairment of TP53-pathway in chronic lymphocytic leukemia

MRÁZ Marek ČERNÁ Kateřina MUSILOVÁ Kateřina MALČÍKOVÁ Jitka PLEVOVÁ Karla PAVLOVÁ Šárka TICHÝ Boris BRYCHTOVÁ Yvona DOUBEK Michael MAYER Jiří TRBUŠEK Martin POSPÍŠILOVÁ Šárka

Conference abstract

Year: 2013, type: Conference abstract
The expression of micrRNA-34a is a highly reliable for impairment of p53-pathway in CLL: development of clinically applicable assay

MRÁZ Marek ČERNÁ Kateřina MUSILOVÁ Kateřina MALČÍKOVÁ Jitka PLEVOVÁ Karla PAVLOVÁ Šárka TICHÝ Boris BRYCHTOVÁ Yvona DOUBEK Michael MAYER Jiří TRBUŠEK Martin POSPÍŠILOVÁ Šárka

Conference abstract

Year: 2013, type: Conference abstract

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Teaching