Mgr. Michal Vašina, Ph.D.

2025

• Engineering Dehalogenase Enzymes Using Variational Autoencoder-Generated Latent Spaces and Microfluidics

  KOHOUT Pavel VAŠINA Michal MAJEROVÁ Marika NOVÁKOVÁ Veronika DAMBORSKÝ Jiří BEDNÁŘ David MAREK Martin PROKOP Zbyněk MAZURENKO Stanislav

  Article in Periodical

  JACS AU, year: 2025, volume: 5, edition: 2, DOI

2024

• Nová duální dehalogenáza-luciferáza z hvězdice křehké Amphiura filiformis

  MAJEROVÁ Marika VAŠINA Michal PLUSKAL Daniel SEDLÁČKOVÁ Karolina PROKOP Zbyněk DAMBORSKÝ Jiří MAREK Martin

  Outcomes put into operation (prototype, working sample)

  Year: 2024

• Nová vysoce aktivní luciferáza z hvězdice křehké Amphiura filiformis

  MAJEROVÁ Marika VAŠINA Michal PLUSKAL Daniel SEDLÁČKOVÁ Karolina PROKOP Zbyněk DAMBORSKÝ Jiří MAREK Martin

  Outcomes put into operation (prototype, working sample)

  Year: 2024

2023

• Advancing Enzyme's Stability and Catalytic Efficiency through Synergy of Force-Field Calculations, Evolutionary Analysis, and Machine Learning

  KUNKA Antonín MARQUES Sérgio Manuel HAVLÁSEK Martin VAŠINA Michal VELÁTOVÁ Nikola CENGELOVÁ Lucia KOVÁŘ David DAMBORSKÝ Jiří MAREK Martin BEDNÁŘ David PROKOP Zbyněk

  Article in Periodical

  ACS Catalysis, year: 2023, volume: 13, edition: 19, DOI

• In-depth analysis of biocatalysts by microfluidics: An emerging source of data for machine learning

  VAŠINA Michal KOVÁŘ David DAMBORSKÝ Jiří YUN Ding YANG Tianjin DE MELLO Andrew MAZURENKO Stanislav STAVRAKIS Stavros PROKOP Zbyněk

  Article in Periodical

  Biotechnology Advances, year: 2023, volume: 66, edition: September 2023, DOI

2022

• Advanced database mining of efficient haloalkane dehalogenases by sequence and structure bioinformatics and microfluidics

  VAŠINA Michal VAŇÁČEK Pavel HON Jiri KOVÁŘ David FALDYNOVÁ Hana KUNKA Antonín BURYŠKA Tomáš BADENHORST Christoffel P. S. MAZURENKO Stanislav BEDNÁŘ David STAVRAKIS Stavros BORNSCHEUER Uwe T. DEMELLO Andrew DAMBORSKÝ Jiří PROKOP Zbyněk

  Article in Periodical

  Chem Catalysis, year: 2022, volume: 2, edition: 10, DOI

• MicroPEX Data Analyser 1.0*

  KOVÁŘ David MAZURENKO Stanislav VAŠINA Michal DAMBORSKÝ Jiří PROKOP Zbyněk

  Software

  Year: 2022

• Tools for computational design and high-throughput screening of therapeutic enzymes

  VAŠINA Michal VELECKÝ Jan PLANAS IGLESIAS Joan MARQUES Sérgio Manuel ŠKAŘUPOVÁ Jana DAMBORSKÝ Jiří BEDNÁŘ David MAZURENKO Stanislav PROKOP Zbyněk

  Article in Periodical

  ADVANCED DRUG DELIVERY REVIEWS, year: 2022, volume: 183, edition: April 2022, DOI

2021

• Computational Enzyme Stabilization Can Affect Folding Energy Landscapes and Lead to Catalytically Enhanced Domain-Swapped Dimers

  MARKOVÁ Klára KUNKA Antonín CHMELOVÁ Klaudia HAVLÁSEK Martin BABKOVÁ Petra MARQUES Sérgio Manuel VAŠINA Michal PLANAS IGLESIAS Joan CHALOUPKOVÁ Radka BEDNÁŘ David PROKOP Zbyněk DAMBORSKÝ Jiří MAREK Martin

  Article in Periodical

  ACS Catalysis, year: 2021, volume: 11, edition: 21, DOI

• Engineering the protein dynamics of an ancestral luciferase

  SCHENKMAYEROVÁ Andrea RANGEL PAMPLONA PIZARRO PINTO José Gaspar TOUL Martin MAREK Martin HERNYCHOVÁ Lenka PLANAS IGLESIAS Joan LIŠKOVÁ Veronika PLUSKAL Daniel VAŠINA Michal EMOND Stephane DÖRR Mark CHALOUPKOVÁ Radka BEDNÁŘ David PROKOP Zbyněk HOLLFELDER Florian BORNSCHEUER Uwe T. DAMBORSKÝ Jiří

  Article in Periodical

  Nature Communications, year: 2021, volume: 12, edition: 1, DOI