Project information
National Institute of Virology and Bacteriology
(NIVB)
- Project Identification
- LX22NPO5103
- Project Period
- 6/2022 - 12/2025
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- national recovery plan
- 5.1 EXCELES
- MU Faculty or unit
-
Central European Institute of Technology
- prof. RNDr. Robert Vácha, PhD.
- Mgr. Gabriel Demo, Ph.D.
- Mgr. Martina Drabinová
- Francesco Luca Falginella, Ph.D.
- Ing. Tibor Füzik, Ph.D.
- Mgr. Mária Gondová
- Ing. et Ing. Miroslav Haman
- Mgr. Adelheid Hanáčková
- Ing. Ondřej Kroutil, Ph.D.
- Timothée Emmanuel Jonathan Rivel, Ph.D.
- Mgr. Jana Salamonová
- prof. RNDr. Robert Vácha, PhD.
- Other MU Faculty/Unit
- Faculty of Medicine
- Other MU Faculty/Unit
-
Faculty of Science
- prof. RNDr. Roman Pantůček, Ph.D.
- Mgr. Tibor Botka, Ph.D.
- Lenka Buňatická
- prof. RNDr. Jiří Doškař, CSc.
- Mgr. Adéla Finstrlová, Ph.D.
- Mgr. Jiřina Havránková
- Mgr. Vojtěch Kovařovic, Ph.D.
- Mgr. Lucie Kuntová, Ph.D.
- Mgr. Ivana Mašlaňová, Ph.D.
- Mgr. Michal Zeman, Ph.D.
- Cooperating Organization
-
Institute of Microbiology of the ASCR, v. v. i.
Institute of Molecular Genetics of the ASCR, v. v. i.
Institute of Organic Chemistry and Biochemistry of the ASCR, v. v. i.
- Responsible person RNDr. PhDr. Zdeněk Hostomský, CSc.
Palacký University, Olomouc
Prague Institute of Chemical Technology
Biological Centre of the ASCR, v. v. i.
Basic and oriented or clinical research on viruses and pathogenic bacteria is essential to understand the processes by which they cause disease, how they escape the immune system and how they can resist treatment. Therefore, research activities at the National Institute of Virology and Bacteriology will focus on characterizing pathogens causing existing and emerging infectious diseases, describing virus and bacteria interactions with the host, understanding the molecular mechanisms of pathogenesis, and developing antiviral and antibacterial agents and vaccines. Individual research groups will work on viruses and bacteria causing diseases with significant health and economic impact, including HIV-1, influenza, tick-borne encephalitis, hepatitis B, SARS-CoV-2, enteroviruses, and the bacteria B. pertussis, S. aureus, and T. pallidum. By working with pathogens that are relevant to current clinical practice, the research groups will have the expertise and equipment for the ongoing study of new pathogens that could become prevalent in the human population in the future.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 117
2023
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Characterization of a transitionally occupied state and thermal unfolding of domain 1.1 of σ A factor of RNA polymerase from Bacillus subtilis
Proteins: Structure, Function and Bioinformatics, year: 2023, volume: 91, edition: 9, DOI
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Identification of phage defence systems targeting other viruses infecting bacterial hosts
Year: 2023, type: Conference abstract
-
In vitro cultivation of Treponema Pallidum: New tool to study physiology and genetics of the syphilis agent
Year: 2023, type: Conference abstract
-
INTERPLAY BETWEEN VIRAL TRANSCRIPTION AND HOST TRANSLATION
Year: 2023, type: Conference abstract
-
Jorvik: a membrane-containing phage that will likely found a new family within Vinavirales
iScience, year: 2023, volume: 26, edition: 11, DOI
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Liquid-liquid phase separation of a bacterial translation factor
Year: 2023, type: Conference abstract
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Low genetic diversity of Treponema pallidum ssp. pertenue (TPE) isolated from patients’ ulcers in Namatanai District of Papua New Guinea
Year: 2023, type: Appeared in Conference without Proceedings
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Luminální mikrobiota u lidí žijících s HIV – deplece producentů SCFA
Year: 2023, type: Conference abstract
-
Membrane adsorption enhances translocation of antimicrobial peptide buforin 2
Year: 2023, type: Conference abstract
-
Model Sugars Right: Improved Interactions of Glycans in All-Atom Molecular Dynamics Simulations
Year: 2023, type: Conference abstract