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Project information
New photoactivatable systems for biological studies

Project Identification
ME09021
Project Period
4/2009 - 12/2012
Investor / Pogramme / Project type
Ministry of Education, Youth and Sports of the CR
  • Programme KONTAKT (ME+MEB)
  • Research and Development Programme KONTAKT (ME)
MU Faculty or unit
Faculty of Science
Keywords
Photochemistry

Photoactivatable compounds (also called caged compounds) are systems which, upon photoactivation, either (1) irreversibly release a species possessing desirable physical, chemical, or biological qualities, while the groups that are responsible for the photoprocess are referred to as photoremovable; or (2) reversibly induce physical or chemical changes in a system; in such cases, they are called photochemical switches and the process is usually photochromic (photochromism is a reversible chemical transformation, induced in one or both directions by the absorption of light, between two forms having different absorption spectra and other photophysical properties). Photoactivatable compounds are of a great interest in connection with biochemical and biological applications (e.g., photoregulations of proteins and enzyme activity, neurotransmitters, ATP, and Ca2+ delivery, or photoactivatable fluorophores), organic synthesis (e.g., photoremovable protecting groups; solid-phase synthesis; microarray fabrica

Publications

Total number of publications: 7

2013

2012

2011

2010

2009

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